HAI Book 2025 - Flipbook - Page 11
123 Astrocyte reactivity explains taurelated effects on hippocampal
dysfunction and longitudinal atrophy in
preclinical Alzheimer9s disease ............ 554
Cody, Karly ......................................... 578
133 Effects of amyloid and tau status on
multiplex plasma CNS and innammatory
proteins in a normal aging cohort ......... 578
Yang, Hyun-Sik................................... 557
Gogola, Alexandra............................... 581
124 Plasma phosphorylated tau 217 and
longitudinal trajectories of A´, tau, and
cognition in cognitively unimpaired older
adults ................................................. 557
134 Tau imaging thresholds within NIA-AA
multilevel tau staging as predictors of tau
accumulation and cognitive decline in nondemented individuals ........................... 581
Rissman, Robert ................................. 561
Smith, Anna........................................ 585
125 Detection of TDP-43 from plasmaderived astrocyte extracellular vesicles for
identiocation of LATE .......................... 561
135 Multi-morbidity and Alzheimer9s
disease pathology across the lifespan in
adults with Down syndrome ..................585
Winer, Joseph .................................... 562
Schwartz, Daniel ................................ 587
126 Short sleep duration is associated
with higher subsequent plasma p-tau217 in
aging .................................................. 562
136 Cortical atrophy is correlated with the
discrepancy between neuroradiological
assessment and binary quantitation of
norbetapir PET in nondemented older
adults .................................................. 587
Sai, Isha .............................................. 564
127 Impacts of testing language and rates
of amyloid positivity among
underrepresented groups in the A4 Study
........................................................... 564
Wiklund, Emma E ............................... 567
128 Lower locus coeruleus metabolism is
associated with greater year-to-year
intraindividual cognitive variability in older
individuals with elevated levels of
Alzheimer9s disease pathology ............. 567
Silva-Rodríguez, Jesús ...................... 570
129 Long-term cognitive and biomarker
trajectories of cognitively unimpaired
individuals with elevated plasma ptau-217
........................................................... 570
Schwarz, Christopher ......................... 571
130 A large public release of PIB PET and
MRI from the Mayo Clinic Study of Aging 571
Ruppert, Emma .................................. 573
131 Harmonizing visual readings of
Flortaucipir and MK-6240 using head-tohead data............................................ 573
Wu, Chao-Yi ........................................577
132 Twin-mapping techniques in clinical
trials: a proof-of-concept application to
the Internet-Based Conversational
Engagement Clinical Trial (I-CONECT) ...577
HAI2025 - 11
Silva Oliveira Junior, Markley ............. 590
137 Vascular pathology innuences the
association of tau-PET with
neurodegeneration and cognition in A´negative individuals ............................ 590
Van Egroo, Maxime............................. 594
138 Concomitant neurodegeneration of
the lateral hypothalamus and locus
coeruleus is associated with early
Alzheimer9s disease-related
pathophysiological and cognitive
processes........................................... 594
Roemer-Cassiano, Sebastian Niclas . 598
139 Amyloid-associated hyperconnectivity
drives tau spreading across connected
brain regions in Alzheimer9s disease .... 598
Saha, Pampa ...................................... 602
140 Association of plasma GFAP with tau
PET in cognitively unimpaired A´-negative
subjects ............................................. 602
McLachlan, Max.................................. 605
141 The striatum is an early, accurate
indicator of [C-11]PiB amyloid burden for
the Down syndrome population ........... 605
Tissot, Cécile ..................................... 608
