HAI Book 2025 - Flipbook - Page 367
Hanseeuw, Bernard
82
In low neocortical tau individuals, high amygdala tau predicts faster
cognitive decline
Bernard Hanseeuw1,2, Emma Thibault1, Michelle Farell1, Rachel Buckley1, Michael Properzi1,
Jennifer Gatchel1, Rebecca Amariglio1, Gad Marshall1, Alexa Beiser4, Sudha Seshadri3, Charles
De Carli5, Reisa Sperling1, Heidi Jacobs1, Keith Johnson1
1
Mass General Brigham, Boston, MA, US
Cliniques Universitaires Saint-Luc, Brussels, BE
3
University of Texas Health San Antonio, San Antonio, TX, US
4
Boston University, Boston, MA, US
5
University of California Davis, Davis, CA, US
2
Background: Recent clinical trials have used low signal in temporal neocortex (tau-PET stage
