HAI Book 2025 - Flipbook - Page 46
Division of Clinical Geriatrics, Center of
Alzheimer Research, Stockholm, SE
03:55 pm - 04:50 pm
Poster Session 2B
04:50 pm - 06:15 pm
SESSION VI Heterogeneity
Sylvia Villeneuve, McGill University, Montreal,
QC, Canada
David Wolk, Penn Memory Center, Philadelphia,
PA, USA
04:50 pm - 04:55 pm
Session Overview
Chairs
4:55 pm
5:10 pm
Improving history-based prediction of
biomarker and clinical progression of
autosomal dominant Alzheimer9s disease using
mutation-level analysis of A´ production
Tau PET load in early- and late-onset
Alzheimer9s disease: A cross-sectional and
longitudinal comparison of the LEADS and
ADNI cohorts
Stephanie Schultz, Harvard Medical School,
Cambridge, MA, US
Konstantinos Chiotis, University of California
San Francisco, San Francisco, CA, US
5:25 pm
Regional tau quantification methodologies in
early symptomatic participants with presence
of tau pathology
Diana Otero Svaldi, Eli Lilly and Company,
Indianapolis, IN, US
5:40 pm
Alpha Synuclein co-pathology accelerates
amyloid associated tau accumulation in
Alzheimer9s disease
Nicolai Franzmeier, Institute for Stroke and
Dementia Research (ISD), LMU University
Hospital, Munich, DE
05:55 pm - 06:15 pm
Discussion
Friday, January 17, 2025
08:15 am - 08:45 am
Mentoring Session and Breakfast
09:00 am - 10:40 am
SESSION VII Factors which Influence ATN
Heidi Jacobs, Massachusetts General Hospital,
Boston, MA, USA
Suzanne Schindler, Washington University
School of Medicine in St Louis, St Louis, MO, USA
09:00 am - 09:05 am
Session Overview
Chairs
09:05 am
09:20 am
09:35 am
09:50 am
10:05 am
10:20 am - 10:40 am
Evaluating the ATN framework in a racially and
ethnically diverse cohort: Preliminary analysis
from the Health Aging Brain Study- Health
Disparities Study
Racial and ethnicity differences in plasma
biomarker eligibility prior to amyloid PET
imaging in the AHEAD 3-45 Study
Examining neighborhood disadvantage as a
factor explaining amyloid onset age
Intersections of sex and neighborhood
disadvantage on Alzheimer9s disease
pathology
Sex moderates relationships between PTau217 and longitudinal tau-PET: A multicohort study
Discussion
HAI2025 - 46
Ann Cohen, University of Pittsburgh School of
Medicine, Department of Psychiatry, Pittsburgh,
PA, US
Doris Molina-Henry, Alzheimer's Therapeutic
Research Institute, University of Southern
California, San Diego, CA, US
Margo Heston, Wisconsin Alzheimer's Disease
Research Center, University of Wisconsin School
of Medicine and Public Health, Madison, WI, US
Alexandria Reese, Department of Epidemiology,
University of Pittsburgh, Pittsburgh, PA, US
Gillian Coughlan, Department of Neurology,
Massachusetts General Hospital, Harvard
Medical School, Boston, MA, US
