HAI Book 2025 - Flipbook - Page 500
Cohen, Ann
Evaluating the ATN framework in a racially and ethnically diverse cohort:
Preliminary analysis from the Health Aging Brain Study- Health Disparities
Study
Ann D. Cohen1, Michael C. Donohue2, Beau Ances3, Karin L. Meeker4, Julie Wisch3, Meredith N.
Braskie5, Melissa Petersen4, Leigh A Johnson4, Robert A. Rissman2, Arthur W. Toga5, Kristine
Yaffe6, Sid O9Bryant4
1
University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, PA, PA, US
Alzheimer’s Therapeutic Research Institute, University of Southern California, San Diego, CA, US
3
Washington University School of Medicine Department of Neurology, St. Louis, MO, US
4
University of North Texas, Health Science Center, Fort Worth, TX, US
5
University of Southern California, Stevens Neuroimaging and Informatics Institute, Los Angeles, CA, US
6
University of California, San Francisco; Weill Institute for Neurosciences, San Francisco, CA, US
2
A key concept underlying Alzheimer9s disease (AD) is the presence of A´ (A). This preclinical stage of AD is
expected to progress to neocortical Tau (T), neurodegeneration (N), and dementia. However, this