HAI Book 2025 - Flipbook - Page 53
Comparison of distribution volume and
standardized uptake value ratio for a MAO-B
tracer in mild cognitive impairment
Association between early and late tau
aggregation across tau imaging agents: The
HEAD Study
The impact of spatial smoothing on the accuracy
of Centiloid thresholds
Longitudinal amyloid PET trajectories in the
HABS-HD cohort
Gleb Bezgin, McGill University, Montreal, QC,
CA
Nesrine Rahmouni, McGill University, Montreal,
QC, CA
Alfonso Fajardo-Valdez, Douglas Mental
Health University Institute, Montreal, Quebec,
Canada, Montreal, QC, CA
Tobey Betthauser, University of WisconsinMadison, School of Medicine and Public Health,
Department of Medicine, Madison, WI, US
Lower microstructural integrity of the locus
coeruleus to entorhinal cortex pathway is
related to elevated astrocyte reactivity and
tau burden in cognitively unimpaired
individuals: a 7T dMRI study
Yuliya Patsyuk, Faculty of Health, Medicine
and Life Sciences, Mental Health and
Neuroscience Research Institute, Alzheimer
Centre Limburg, Maastricht University,
Maastricht, NL
11:35 am - 01:00 pm
SESSION II Spatial Patterns
Ansel Hillmer, University of Michigan , Ann
Arbor, MI, USA
Pedro Rosa-Neto, McGill University, Montreal,
QC, Canada
11:35 am - 11:40 am
Session Overview
Chairs
11:40 am
11:55 am
The interaction of initial medial temporal lobe
tauopathy and amyloid-beta spatial extent in
driving caTAUstrophe
Mapping spatial white matter integrity linked to
tau accumulation: Insights from tractometry
with multi-shell diffusion imaging
12:10 am
Spatial patterns of voxel-wise tau accumulation
across the Alzheimer9s disease spectrum
12:25 am
PET astroglia and microglia follow tau
propagation patterns in Alzheimer9s Disease
12:40 pm - 01:00 pm
Discussion
01:00 pm - 02:00 pm
Lunch break
02:00 pm - 02:30 pm
KEYNOTE: From click chemistry to precision
neuroscience
02:30 pm - 02:45 pm
Keynote Discussion
Michelle Farrell, Massachusetts General
Hospital, Boston, MA, US
Dana Parker, University of California Irvine,
Irvine, CA, US
Corrina Fonseca, Department of
Neuroscience, University of California
Berkeley, Berkeley, CA, US
Nesrine Rahmouni, McGill University, Montreal,
QC, CA
Hartmuth Kolb, Enigma Biomedical Group
02:45 pm - 04:25 pm
SESSION III Neuropath I
Tobey Betthauser, University of Wisconsin
School of Medicine and Public Health, Madison,
WI, USA
Teresa Gomez-Isla, Massachusetts General
Hospital, Boston, MA, USA
02:45 pm - 02:50 pm
Session Overview
Chairs
2:50 pm
Correlation between in vivo 18F-flortaucipir PET
and whole brain postmortem histological tau
signals in Alzheimer9s Disease
Yishu Chao, University of California Berkeley,
Berkeley, CA, US
3:05 pm
Tau-PET, structural MRI, and cognitive measures
are differentially correlated with tangle and
Christina Moloney, Department of
Neuroscience, Mayo Clinic, Jacksonville, FL,
US
HAI2025 - 53
