HAI Book 2025 - Flipbook - Page 59
02:10 pm - 02:25 pm
Keynote Discussion
02:25 pm - 03:50 pm
SESSION V Clinically Relevant Applications
Renaud La Joie, University of California, San
Francisco. San Francisco, CA, USA
Reisa Sperling, Brigham and Women's Hospital,
Boston, MA, USA
02:25 pm - 02:30 pm
Session Overview
Chairs
2:30 pm
2:45 pm
Neuropathologic and ARIA-related findings in
aducanumab-treated Alzheimer's disease: a
postmortem analysis of superficial cortical A´
clearance
Robustness of the centiloid scale across
research and commercial software using
[18F]flutemetamol PET images
3:00 pm
Impact of ARIA on cerebral volume changes with
Gantenerumab
3:15 pm
Independent effects of baseline white matter
hyperintensity and APOE ɛ4 on future ARIA-H
emergence in A4 trial
03:30 pm - 03:50 pm
Discussion
03:50 pm - 03:55 pm
Blitz Session 2B Short Poster Presentations
3:50 pm
Introduction
3:52 pm
Cortical freewater increases with tau tangle
aggregation
3:53 pm
Two distinct sources of 18F-MK-6240 off-target
signal identified by individualized head modeling
and PET kinetics
3:54 pm
Tracking plasma biomarker abnormalities with
amyloid time accumulation
03:55 pm - 04:50 pm
Baayla Boon, Department of Neuroscience,
Jacksonville, FL, US
Adam Schwarz, GE HealthCare, Chalfont St.
Giles, GB
Matteo Tonietto, Research and Early
Development (pRED), Hoffmann-La Roche,
Basel, CH
Zahra Shirzadi, Department of Neurology,
Massachusetts General Hospital, Brigham and
Women's Hospital, Harvard Medical School,
Boston, MA, US
Brandon Hall, McGill University, Montreal, QC, CA
Charles Chen, Athinoula A. Martinos Center for
Biomedical Imaging, Massachusetts General
Hospital, Charlestown, MA, US
Marina Bluma, Karolinska Institutet, Department
of Neurobiology, Care Sciences and Society,
Division of Clinical Geriatrics, Center of
Alzheimer Research, Stockholm, SE
Poster Session 2B
04:50 pm - 06:15 pm
SESSION VI Heterogeneity
Sylvia Villeneuve, McGill University, Montreal,
QC, Canada
David Wolk, Penn Memory Center, Philadelphia,
PA, USA
04:50 pm - 04:55 pm
Session Overview
Chairs
4:55 pm
5:10 pm
Improving history-based prediction of
biomarker and clinical progression of autosomal
dominant Alzheimer9s disease using mutationlevel analysis of A´ production
Tau PET load in early- and late-onset
Alzheimer9s disease: A cross-sectional and
longitudinal comparison of the LEADS and ADNI
cohorts
HAI2025 - 59
Stephanie Schultz, Harvard Medical School,
Cambridge, MA, US
Konstantinos Chiotis, University of California
San Francisco, San Francisco, CA, US
