HAI Book 2025 - Flipbook - Page 636
Conclusions: Inter-tracer agreement is especially low in early Braak regions. The four tracers presented
substantial ordinal agreement and poor categorical agreement for in vivo Braak staging. Slight improvements in
agreements were achieved with the simplified framework, as observed in histopathological staging.
Keywords: Braak staging; positron emission tomography; neurofibrillary tangles; Alzheimer’s disease; staging
HAI2025 - 636